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cis-Urocanic acid

CAS No. 7699-35-6

cis-Urocanic acid ( (Z)-Urocanic acid; cis-UCA; (E)-Urocanic acid; (Z)-Imidazole-4-acrylic acid; (Z)-3-(1H-Imidazol-5-yl)acrylic acid )

产品货号. M26118 CAS No. 7699-35-6

cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥3750 有现货
10MG ¥5532 有现货
25MG ¥8667 有现货
50MG ¥11745 有现货
100MG ¥15795 有现货
500MG ¥31509 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    cis-Urocanic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
  • 产品描述
    cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.(In Vitro):Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion decreases caspase-3 activity and improves cell viability against UV-B irradiation. No significant effects on IL-6 or IL-8 secretion, caspase-3 activity, or viability of the non-irradiated cells are observed with 100 μg/mL cis-Urocanic acid in both cell types .
  • 同义词
    (Z)-Urocanic acid; cis-UCA; (E)-Urocanic acid; (Z)-Imidazole-4-acrylic acid; (Z)-3-(1H-Imidazol-5-yl)acrylic acid
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    Alkyl-Chain
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    7699-35-6
  • 分子量
    138.1
  • 分子式
    C6H6N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OC(=O)\C=C/c1cnc[nH]1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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